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Cat. No. Product Name Target Signaling Pathways
T14694 BNC105

Microtubule Associated Cytoskeletal Signaling
BNC105 是一种微管蛋白聚合抑制剂,具有抗增殖和破坏肿瘤血管的特性。
T68273 BNC105P

BNC105P is a benzofuran-based vascular disrupting agent (VDA) prodrug with potential anti-vascular and antineoplastic activities. Upon administration vascular disrupting agent BNC105P, the disodium phosphate ester of BNC105, is rapidly converted to BNC105; in activated endothelial cells, BNC105 binds to tubulin and inhibits its polymerization, which may result in a blockage of mitotic spindle formation, cell cycle arrest, and disruption of the tumor vasculature. Hypoxic conditions ensue, deprivi...

化合物

BNC105
Cat.No: T14694
Synonym:
Target: Microtubule Associated
BNC105P
Cat.No: T68273
Synonym:
Target:
TargetMol Loading
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