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Cat. No. Product Name Target Signaling Pathways
T70389 BMS986126

BMS-986122 is a IRAK4 Inhibitor. BMS-986126 attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity. BMS-986126 inhibited TLR7- and TLR9-dependent responses using cells derived from lupus patients, suggesting that inhibition of IRAK4 has the potential for therapeutic benefit in treating lupus.
T70388 (S)-Enitociclib

VIP152

CDK Cell Cycle/Checkpoint
(S)-Enitociclib (VIP152) 是一种选择性 CDK9 抑制剂,通过抑制 RNA 聚合酶 II 介导的转录来诱导 MYC+ 淋巴瘤的完全消退,抑制抗凋亡和促生存蛋白的转录。

化合物

BMS986126
Cat.No: T70389
Synonym:
Target:
(S)-Enitociclib
Cat.No: T70388
Synonym: VIP152
Target: CDK
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