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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T38164 MnTBAP chloride

Mn(III)TBAP

MnTBAP chloride (Mn(III)TBAP) 是一种具有细胞渗透性的超氧化物歧化酶 (SOD) 模拟物和过氧亚硝酸盐清除剂,能使SOD-大肠杆菌的加倍时间减少了2倍。 MnTBAP chloride 通过上调 BMPR-II 和抑制 NFκB 信号传导展现抗炎作用。MnTBAP chloride 是一种锰卟啉配合物,具有抗氧化性能,具有用于研究慢性肾脏疾病 (CKDs) 纤维化反应的潜力。

化合物

MnTBAP chloride
Cat.No: T38164
Synonym: Mn(III)TBAP
Target:
Cat. No. Product Name Species Expression System
TMPY-01059 BMPR2 Protein, Human, Recombinant (His)

POVD1,PPH1,BMPR3,BRK-3,BMPR-II,bo...

Human HEK293 Cells
BMPR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.6 kDa and the accession number is Q13873.
TMPY-00683 BMPR2 Protein, Human, Recombinant (His & hFc)

BMPR3,BRK-3,PPH1,BMPR-II,bone mor...

Human HEK293 Cells
BMPR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 42 kDa and the accession number is Q13873.
TMPK-01152 CHRDL1 Protein, Human, Recombinant (His)

VOPT,Ventroptin,Neuralin-1,dA141H5.1,CHL,Chordin-like 1,CRDL...

Human E. coli
CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved in carcinogenesis and metastasis.The hypermethylation of the CHRDL1 promoter in gastric cancer, which induced low expression of CHRDL1 and decreased its secretion to the supernatant.
TMPJ-00966 GDF-5 Protein, Human, Recombinant

Lipopolysaccharide-associated protein 4,Cartilage-derived mo...

Human E. coli
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor protein consisting of a 354 amino acid (aa) Nterminal proregion and a 120 aa C-terminal mature peptide. Mature human GDF-5 shares 99% aa sequence identity with both mature mouse and rat GDF-5. GDF-5 signaling is mediated by formation of a heterodimeric complex consisting of a ty...

重组蛋白

BMPR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01059
Species: Human
Expression System: HEK293 Cells
BMPR2 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00683
Species: Human
Expression System: HEK293 Cells
CHRDL1 Protein, Human, Recombinant (His)
Cat.No: TMPK-01152
Species: Human
Expression System: E. coli
GDF-5 Protein, Human, Recombinant
Cat.No: TMPJ-00966
Species: Human
Expression System: E. coli
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