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Cat. No. Product Name Target Signaling Pathways
T79418 BLT2 antagonist-1

Leukotriene Receptor GPCR/G Protein
BLT2 agonist-1 (compound 15b) 是选择性BLT2拮抗剂,能在224 nM IC50下抑制CHO-BLT2细胞趋化性。它不影响CHO-BLT1细胞趋化性,并在132 nM Ki值下抑制LTB4与BLT2结合。BLT2 agonist-1适用于哮喘、慢性阻塞性肺病等炎症性气道疾病研究。
T37260 14,15-dehydro Leukotriene B4

14,15-dehydro Leukotriene B4

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value ...

化合物

BLT2 antagonist-1
Cat.No: T79418
Synonym:
Target: Leukotriene Receptor
14,15-dehydro Leukotriene B4
Cat.No: T37260
Synonym: 14,15-dehydro Leukotriene B4
Target:
TargetMol Loading
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