Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26809 |
BIIL 260
BIIL260,BIIL-260 |
||
BIIL 260 is a leukotriene B4 (BLT1) receptor antagonist with anti-inflammatory activity. | |||
T10543 |
BIIL-260 hydrochloride
|
Others | Others |
BIIL-260 hydrochloride is a potent and long-acting orally active antagonist of leukotriene B4 (LTB4) receptor with anti-inflammatory activity. It has a high affinity to the LTB4 receptor on isolated human neutrophil cell membranes (Ki: 1.7 nM). | |||
T14210 |
Amelubant
BIIL 284 |
LTR | Immunology/Inflammation |
Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1]. Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 receptor, with Kis of 221 nM and 230 nM |