Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10477 |
BAY-985
|
IκB/IKK | NF-κB |
BAY-985 是高效的、ATP 竞争性的、有口服活性的、选择性的TBK1和IKKε双重抑制剂,对 TBK1 (在低/高 ATP 实验中) 和 IKKε 的IC50分别为 2/30 和 2 nM。它具有抗肿瘤作用。 | |||
T12659 | (Rac)-BAY-985 | IκB/IKK | NF-κB |
(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy. |