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Cat. No. | Product Name | Target | Signaling Pathways |
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T78287 |
Alsevalimab
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Alsevalimab为针对B7-H4的人源化单克隆抗体。 | |||
T81345 |
Puxitatug
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Puxitatug是一种针对[Homo sapiens VTCN1 (包含T细胞激活抑制剂1、B7家族成员H4、B7H4、B7-H4的Vset结构域)]的Homo sapiens免疫球蛋白G1-κ型单克隆抗体。 | |||
T74735 |
Gly-Cyclopropane-Exatecan
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Gly-Cyclopropane-Exatecan (compound 5c) 参与合成抗 B7-H4抗体活性分子缀合物 (ADC),含有 DNA 拓扑异构酶 I (TopoisomeraseI) 抑制剂 Exatecan 。Gly-Cyclopropane-Exatecan 参与形成的 ADC 为 hu2F7-Exatecan (compound 34) 具有体内外抗肿瘤活性。 |
Cat. No. | Product Name | Species | Expression System |
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TMPY-03524 |
B7-H4 Protein, Human, Recombinant (His)
PRO1291,B7X,B7H4,B7-... |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1. | |||
TMPY-05280 |
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated
B7S1,B7X,VCTN1,B7h.5,V-set domain... |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1. | |||
TMPJ-00175 |
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
V-set domain containing T cell activation inhibitor 1,B7... |
Rhesus | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the s... | |||
TMPK-00172 |
B7-H4 Protein, Human, Recombinant (His & Avi)
B7H4,B7x,VTCN1,PRO1291,B7 |
Human | HEK293 Cells |
B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status . | |||
TMPY-05080 |
B7-H4 Protein, Human, Recombinant (mFc)
B7H4,VCTN1,V-set domain containing T cell ... |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.7 kDa and the accession number is Q7Z7D3-1. | |||
TMPY-03009 |
B7-H4 Protein, Human, Recombinant (hFc)
B7h.5,B7X,PRO1291,B7S1,B7 |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1. | |||
TMPY-05281 |
B7-H4 Protein, Human, Recombinant (His), Biotinylated
PRO1291,VCTN1,B7S1,B7h.5,B7-H... |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1. | |||
TMPJ-00176 |
B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
B7H4T-cell costimulatory molecule B7 |
Human | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two Ig-like V-type domains, a 21 aa transmembrane segment, and a 2 aa cytoplasmic tail. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine ... | |||
TMPY-05611 |
B7-H4 Protein, Human, Recombinant (His & Avi), Biotinylated
PRO1291,B7X,V-set domain containing T cell activati... |
Human | HEK293 Cells |
B7-H4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.6 kDa and the accession number is Q7Z7D3-1. | |||
TMPY-05322 |
B7-H4 Protein, Mouse, Recombinant (His)
BC032925,B7h4,B7x,V-set domain co... |
Mouse | HEK293 Cells |
B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is Q7TSP5. | |||
TMPY-06074 |
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
V-set domain containing T cell activation inhibitor 1 |
Cynomolgus,Rhesus | HEK293 Cells |
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A2K5U6P5-1. | |||
TMPY-02658 |
B7-H4 Protein, Mouse, Recombinant (hFc)
B7h4,BC032925,B7x,B7s1,V... |
Mouse | HEK293 Cells |
B7-H4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is Q7TSP5. |