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3

抑制剂 & 化合物

12

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T78287 Alsevalimab

Alsevalimab为针对B7-H4的人源化单克隆抗体。
T81345 Puxitatug

Puxitatug是一种针对[Homo sapiens VTCN1 (包含T细胞激活抑制剂1、B7家族成员H4B7H4B7-H4的Vset结构域)]的Homo sapiens免疫球蛋白G1-κ型单克隆抗体。
T74735 Gly-Cyclopropane-Exatecan

Gly-Cyclopropane-Exatecan (compound 5c) 参与合成抗 B7-H4抗体活性分子缀合物 (ADC),含有 DNA 拓扑异构酶 I (TopoisomeraseI) 抑制剂 Exatecan 。Gly-Cyclopropane-Exatecan 参与形成的 ADC 为 hu2F7-Exatecan (compound 34) 具有体内外抗肿瘤活性。

化合物

Alsevalimab
Cat.No: T78287
Synonym:
Target:
Puxitatug
Cat.No: T81345
Synonym:
Target:
Gly-Cyclopropane-Exatecan
Cat.No: T74735
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-03524 B7-H4 Protein, Human, Recombinant (His)

PRO1291,B7X,B7H4,B7-...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1.
TMPY-05280 B7-H4 Protein, Human, Recombinant (hFc), Biotinylated

B7S1,B7X,VCTN1,B7h.5,V-set domain...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1.
TMPJ-00175 B7-H4 Protein, Rhesus macaque, Recombinant (hFc)

V-set domain containing T cell activation inhibitor 1,B7...

Rhesus HEK293 Cells
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the s...
TMPK-00172 B7-H4 Protein, Human, Recombinant (His & Avi)

B7H4,B7x,VTCN1,PRO1291,B7

Human HEK293 Cells
B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status .
TMPY-05080 B7-H4 Protein, Human, Recombinant (mFc)

B7H4,VCTN1,V-set domain containing T cell ...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.7 kDa and the accession number is Q7Z7D3-1.
TMPY-03009 B7-H4 Protein, Human, Recombinant (hFc)

B7h.5,B7X,PRO1291,B7S1,B7

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is Q7Z7D3-1.
TMPY-05281 B7-H4 Protein, Human, Recombinant (His), Biotinylated

PRO1291,VCTN1,B7S1,B7h.5,B7-H...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1.
TMPJ-00176 B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated

B7H4T-cell costimulatory molecule B7

Human HEK293 Cells
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two Ig-like V-type domains, a 21 aa transmembrane segment, and a 2 aa cytoplasmic tail. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine ...
TMPY-05611 B7-H4 Protein, Human, Recombinant (His & Avi), Biotinylated

PRO1291,B7X,V-set domain containing T cell activati...

Human HEK293 Cells
B7-H4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.6 kDa and the accession number is Q7Z7D3-1.
TMPY-05322 B7-H4 Protein, Mouse, Recombinant (His)

BC032925,B7h4,B7x,V-set domain co...

Mouse HEK293 Cells
B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is Q7TSP5.
TMPY-06074 B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)

V-set domain containing T cell activation inhibitor 1

Cynomolgus,Rhesus HEK293 Cells
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A2K5U6P5-1.
TMPY-02658 B7-H4 Protein, Mouse, Recombinant (hFc)

B7h4,BC032925,B7x,B7s1,V...

Mouse HEK293 Cells
B7-H4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is Q7TSP5.

重组蛋白

B7-H4 Protein, Human, Recombinant (His)
Cat.No: TMPY-03524
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05280
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
Cat.No: TMPJ-00175
Species: Rhesus
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00172
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05080
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03009
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05281
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPJ-00176
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05611
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05322
Species: Mouse
Expression System: HEK293 Cells
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-06074
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
B7-H4 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02658
Species: Mouse
Expression System: HEK293 Cells
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