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抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T81922	LM2I
	LM2I是一种多杀菌素(SPA)衍生物，兼具精氨酸琥珀酸合成酶(ASS1)激活剂和针对ASS1的直接作用的肿瘤抑制剂功能。在7种结直肠癌细胞系和结直肠癌异种移植肿瘤中，LM2I展现出明显的抗增殖活性，并且通过EGFR途径阻断结直肠癌细胞增长。

化合物

Cat.No: T81922

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00732	ASS1 Protein, Human, Recombinant (His) Citrulline--Aspartate Ligase,Argininosuccinate Synthase,...	Human	E. coli
	Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullin...
TMPH-02527	ASS1 Protein, Mouse, Recombinant (His & Myc) Ass,Citrulline--aspartate ligase,Ass1<...	Mouse	E. coli
	One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. ASS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 5...
TMPY-03172	Argininosuccinate lyase Protein, Human, Recombinant (His & GST) ASAL,argininosuccinate lyase,ASL	Human	Baculovirus Insect Cells
	The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established role in numerous physiological and pathological processes, but the specific cellular sources of NO in disease pathogenesis remain unclear, preventing the implementation of NO-related therapy. Argininosuccinate lyase (ASL) is the only enzyme able to produce arginine, the substrate ...

重组蛋白

ASS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00732

Species: Human

Expression System: E. coli

ASS1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02527

Species: Mouse

Expression System: E. coli

Argininosuccinate lyase Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03172

Species: Human

Expression System: Baculovirus Insect Cells

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