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Search Results for " aporphine "

2

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T70479	Oxonantenine
	Oxonantenine is an oxoaporphine alkaloid isolated from Annona glabra and has been shown to exhibit acetylcholinesterase inhibitory activity. It has a role as a plant metabolite and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is an organic heteropentacyclic compound, an oxacycle, an aromatic ether, an alkaloid antibiotic and an oxoaporphine alkaloid. It derives from an aporphine.
T69139	Thalicarpine
	Thalicarpine is a natural aporphine benzylisoquinoline vinca alkaloid with antineoplastic activity. Thalicarpine binds to and inhibits p-glycoprotein, the multidrug resistance efflux pump. Thalicarpine also induces single-strand breaks in DNA and arrests cancer cells at the G2/M and G1 phase of the cell cycle. Check for active clinical trials or closed clinical trials using this agent.

化合物

Cat.No: T70479

Cat.No: T69139

Cat. No.	Product Name	Target	Signaling Pathways
T3S1319	(+)-Magnoflorine Escholin,Magnoflorine,Thalictrin,Escholine,木兰花碱	Others; Antifungal	Microbiology/Virology; Others
	(+)-Magnoflorine (Thalictrin) 是从 Acoruscalamus 中分到的一种阿朴啡生物碱，可以减少 C. albicans 生物膜的形成，具有抗真菌、抗氧化、抗糖尿病、镇静和抗焦虑的作用。
T3S1320	(+)-Magnoflorine iodide Magnoflorine iodide,Thalictrine iodide,碘化木兰花碱,Corytuberine Methiodide	Others; Antifungal	Microbiology/Virology; Others
	(+)-Magnoflorine iodide (Thalictrine iodide) 是从 Acoruscalamus 中分到的一种阿朴啡生物碱，具有抗炎、抗真菌、抗氧化和抗糖尿病的作用，可以减少C. albicans 生物膜的形成。
T4S1321	(+)-Magnoflorine chloride Magnoflorine chloride,氯化木兰花碱,Corytuberine methochloride,Thalictrine chloride,Escholine chloride	Others; Antifungal	Microbiology/Virology; Others
	(+)-Magnoflorine chloride (Escholine chloride) 是从 Acoruscalamus 中分到的一种阿朴啡生物碱，具有抗炎、抗真菌、抗氧化和抗糖尿病的作用，可以减少 C. albicans 生物膜的形成。
TN6038	1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine
	1,2-Methylenedioxy-3,10,11-trimethoxyaporphine exerts moderate vessel-relaxing activities with the IC 50 value from 16.50 to 32.81 microM at the test concentrations.
TN3169	6-Formyl-1,2,9,10-tetramethoxy-6a,7-dehydroaporphine	Others	Others
	6-Formyl-1,2,9,10-tetramethoxy-6a,7-dehydroaporphine is a natural product from Aconitum carmichaelii.
TN2479	1,2,3,10-Tetramethoxy-9-(2-hydroxy-4,5-dimethoxybenzyloxy)oxoaporphine	Others	Others
	1,2,3,10-Tetramethoxy-9-(2-hydroxy-4,5-dimethoxybenzyloxy)oxoaporphine是一种天然产物，属于莲叶桐科莲叶桐属，其产品编号为 TN2479，CAS号为 872729-33-4。1,2,3,10-Tetramethoxy-9-(2-hydroxy-4,5-dimethoxybenzyloxy)oxoaporphine可用作对照参考。
T83410	2,3,5,6-Tetramethoxyaporphine
	2,3,5,6-Tetramethoxyaporphine 是阿扑啡碱类化合物，具有止咳作用并具药用价值，可从黄角罂粟（Glaucium flavum Cr.，罂粟科）中提取。
TN1210	2-Hydroxy-1-Methoxyaporphine	P450	Metabolism
	2-Hydroxy-1-Methoxyaporphine can inhibit CYP2D6 activity, it also increase the glucose consumption significantly as rosiglitazone.
TQ0296L	N-Nornuciferine hydrochloride(4846-19-9 free base) N-Nornuciferine hydrochloride	P450	Metabolism
	N-Nornuciferine hydrochloride(4846-19-9 free base) (N-Nornuciferine hydrochloride) 是荷叶中的一种 aporphine 生物碱，显着抑制 CYP2D6（IC50：3.76 μM，Ki：2.34 μM）。
TQ0296	N-Nornuciferine	P450	Metabolism
	N-Nornuciferine, an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).
T32567	Lanuginosine Oxoxylopin,NSC-137553,Oxoxylopine,NSC137553,NSC 137553
	Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.
T81587	Oxocrebanine
	Oxocrebanine, 阿朴啡类生物碱，Fissistigma poilanei（番荔枝科）所含。
T83605	(+) N-Methylcorydine
	(+) N-Methylcorydine为一种阿片生物碱，具有阿扑啡结构。
T40469	(+)-N-Formylnorglaucine
	(+)-N-Formylnorglaucine, an aporphine alkaloid found in the leaves of Unonopsis stipitata, features a formyl group that is connected to the nitrogen within its heterocyclic structure.
T75698	Xylopine
	Xylopine 是一种具有细胞毒活性的阿朴啡生物碱，能诱导癌细胞氧化应激，从而引发 G2/M 细胞周期停滞及细胞凋亡(apoptosis)。

天然产物

(+)-Magnoflorine

Cat.No: T3S1319

Synonym: Escholin,Magnoflorine,Thalictrin,Escholine,木兰花碱

Target: Others, Antifungal

(+)-Magnoflorine iodide

Cat.No: T3S1320

Synonym: Magnoflorine iodide,Thalictrine iodide,碘化木兰花碱,Corytuberine Methiodide

Target: Others, Antifungal

(+)-Magnoflorine chloride

Cat.No: T4S1321

Synonym: Magnoflorine chloride,氯化木兰花碱,Corytuberine methochloride,Thalictrine chloride,Escholine chloride

Target: Others, Antifungal

1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine

Cat.No: TN6038

6-Formyl-1,2,9,10-tetramethoxy-6a,7-dehydroaporphine

Cat.No: TN3169

Target: Others

1,2,3,10-Tetramethoxy-9-(2-hydroxy-4,5-dimethoxybenzyloxy)oxoaporphine

Cat.No: TN2479

Target: Others

2,3,5,6-Tetramethoxyaporphine

Cat.No: T83410

2-Hydroxy-1-Methoxyaporphine

Cat.No: TN1210

Target: P450

N-Nornuciferine hydrochloride(4846-19-9 free base)

Cat.No: TQ0296L

Synonym: N-Nornuciferine hydrochloride

Target: P450

N-Nornuciferine

Cat.No: TQ0296

Target: P450

Cat.No: T32567

Synonym: Oxoxylopin,NSC-137553,Oxoxylopine,NSC137553,NSC 137553

Cat.No: T81587

(+) N-Methylcorydine

Cat.No: T83605

(+)-N-Formylnorglaucine

Cat.No: T40469

Cat.No: T75698

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