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Cat. No. | Product Name | Target | Signaling Pathways |
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T38231 |
Isoapoptolidin
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Isoapoptolidin is a stable derivative of apoptolidin that demonstrates 10-fold reduced F1FO-ATP synthase inhibitory activity compared to apoptolidin (IC50s = 17 and 0.7 μM, respectively). |
Cat. No. | Product Name | Target | Signaling Pathways |
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T35605 |
Apoptolidin
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Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsis bacteria. It inhibits the mitochondrial F1FO ATPase (Ki = 4-5 μM). Apoptolidin selectively kills transformed glial cells without significantly affecting untransformed cells. It also has antibiotic and antifungal actions. |