Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1736 |
Apixaban
阿哌沙班,BMS-562247-01 |
Factor Xa | Metabolism |
Apixaban (BMS-562247-01) 是一种高度选择性,可逆的、口服具有活力的凝血因子 Xa (Factor Xa) 抑制剂,抑制人和兔凝血因子 Xa 的 Ki 分别为 0.08 nM 和 0.17 nM。它可以用于研究各种血栓栓塞疾病。 | |||
T10349 |
Apixaban 13C,d3
Apixaban 13CD3,BMS-562247-01 13CD3 |
Others | Others |
Apixaban 13CD3 (BMS-562247-01 13CD3) is a deuterium-labeled Apixaban. Apixaban is a reversible inhibitor of Factor Xa (Ki: 0.08 nM and 0.17 nM in human and rabbit). | |||
T19488 |
O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium (503612-76-8 free base) |
Factor Xa | Metabolism |
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans. | |||
T12279 |
O-Desmethyl apixaban
|
Others | Others |
O-Desmethyl apixaban is a metabolite of Apixaban that is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. | |||
T71429 |
O-Demethyl apixaban sulfate
|
||
O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases. |