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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T36978 AS-99 TFA

AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo[1]. AS-99 TFA is tested against a panel of 20 histone methyltransferases, including NSD1, NSD2, NSD3, and SETD2. NO significant inhibition is observed at 50 μM of AS-99 TFA on any of the tested...
T73529 AS-99

AS-99 是首创的、有效的、选择性 ASH1L 组蛋白甲基转移酶抑制剂 (IC50= 0.79 µM,Kd= 0.89 µM),并具有抗白血病活性。AS-99 阻断细胞增殖,诱导细胞凋亡 (apoptosis) 和细胞分化,下调 MLL 融合靶基因,减少体内白血病负担。

化合物

AS-99 TFA
Cat.No: T36978
Synonym:
Target:
AS-99
Cat.No: T73529
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-01381 ANXA10 Protein, Human, Recombinant

Annexin-10,ANX14,Annexin-14

Human E. coli
Annexin A10 (ANXA10) contains four Annexin repeats and is a member of the Annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is reported that ANXA10 may be a clinical relevant marker for predicting outcome in both early and advanced stages of bladder cancer.

重组蛋白

ANXA10 Protein, Human, Recombinant
Cat.No: TMPJ-01381
Species: Human
Expression System: E. coli
TargetMol Loading
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