Cat. No. | Product Name | Target | Signaling Pathways |
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TP1359L |
Amyloid β Peptide (42-1)(human) acetate
Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base) |
Beta Amyloid | Neuroscience |
Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽,其在阿尔茨海默病的发病机制中起关键作用。 | |||
T37370 |
Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
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Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM.... | |||
T35499 |
β-Amyloid (1-42), (rat/mouse) (TFA)
Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA |
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β-Amyloid (1-42), (rat/mouse) (TFA) 是由 42 个氨基酸组成的多肽片段,可用于研究阿尔茨海默症。 | |||
TP1007 |
β-Amyloid (1-42), human
大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human |
Beta Amyloid | Neuroscience |
β-Amyloid (1-42), human 是一种由 42 个氨基酸组成的肽,在阿尔茨海默病的发病机制中起关键作用。 | |||
TP1359 |
β-Amyloid (42-1), human
Amyloid β Peptide (42-1)(human) |
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β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42) which plays a key role in the pathogenesis of Alzheimer disease. | |||
T80035 |
Biotin-β-Amyloid (1-42), human TFA
Biotin-amyloid β-peptide (1-42) (human) TFA |
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Biotin-β-Amyloid (1-42), human TFA(Biotin-Amyloid β-Peptide (1-42) (human) TFA)是一种标记有生物素的β-Amyloid (1-42)肽,由42个氨基酸构成,对阿尔茨海默病的发病机理有重要作用。 | |||
TP1007L |
β-Amyloid (1-42), acetate (human)
β-Amyloid (1-42), human acetate (107761-42-2 Free base) |
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β-Amyloid (1-42), acetate (human) 是由 42 个氨基酸组成的肽,是 β-Amyloid 的一部分,常用于阿尔茨海默病造模。 | |||
T75926 |
β-Amyloid (42-1), human TFA
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β-Amyloid (42-1), human TFA 为淀粉样蛋白β肽(1-42)的无活性形式,包含42个氨基酸,对阿尔茨海默病发病机制扮演关键角色。 | |||
T80700 |
β Amyloid(17-28) human
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β Amyloid(17-28) human 为β-淀粉样肽(Abeta)的一段核心片段,其结构受脂质诱导。本化合物能够促进β Amyloid40全长肽段的聚集,导致阿尔茨海默病(AD)中具毒性的聚集体形成。 | |||
T80701 |
β Amyloid (1-16) rat
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β-Amyloid (1-16) rat 是β-淀粉样肽 (Abeta) 金属结合域的片段,含有三个与人类相异的氨基酸替代,因此在大鼠和小鼠中降低了 AD 样神经退行性变的易感性。 | |||
T80699 |
β Amyloid(28-35) human
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β Amyloid(28-35) human 是一种具有神经毒性的β-淀粉样肽,能够与神经元膜结合,影响其二级结构并加剧阿尔茨海默病的神经毒性。该肽段对酸性磷脂DPH表现出非均向性作用,从而增加脂质膜双层内部的流动性。该核心片段由脂质诱导形成。 | |||
T36911 |
Pramlintide (acetate hydrate)
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Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human amylin receptor 1a (AMY1a), AMY2a, and AMY3a (EC50s = 0.35, 22.9, and 0.89 nM, respectively). Pramlintide inhibits human islet amyloid polypeptide fibrilization in a concentration-dependent manner. In vivo, pramlintide (200 pg/kg) reduces brain levels of amyloid-β (1-40) and incr... |