购物车

搜索结果

Search Results for " alpha-ctx "

3

抑制剂 & 化合物

2

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name Target Signaling Pathways
T23707 alpha-Conotoxin imi

alpha-Ctx-imi

alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.
T35432 α-Conotoxin ImI (trifluoroacetate salt)

α-Conotoxin ImI is a conotoxin that has been found inC. imperialisand has receptor antagonist and anticancer activities.1It is a peptide antagonist of homomeric α7 nicotinic acetylcholine receptors (nAChRs; IC50= 220 nM). α-Conotoxin ImI is selective for α7 nAChRs over α2β2, α3β2, α4β2, α2β4, α3β4, α4β4, and α1β1γδ subunit-containing nAChRs at 5 μM but does inhibit homomeric α9 nAChRs (IC50= 1,800 nM). Administration of paclitaxel in micelles containing α-conotoxin ImI decreases tumor growth in ...
T23707L alpha-Conotoxin imi acetate(156467-85-5 Free base)

alpha-Conotoxin imi acetate(156467-85-5 Free base) 是一种烟碱乙酰胆碱受体配体。

化合物

alpha-Conotoxin imi
Cat.No: T23707
Synonym: alpha-Ctx-imi
Target:
α-Conotoxin ImI (trifluoroacetate salt)
Cat.No: T35432
Synonym:
Target:
alpha-Conotoxin imi acetate(156467-85-5 Free base)
Cat.No: T23707L
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-03037 Alpha-cobratoxin Protein, Naja kaouthia, Recombinant (GST & His & Myc)

Alpha-CT,Alpha-Ctx,Alpha...

Naja kaouthia E. coli
Monomer: binds with high affinity to muscular (alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND) nAChR (tested on Torpedo californica, Kd=0.2-4.5 nM) and neuronal alpha-7/CHRNA7 nicotinic acetylcholine receptors (Kd=13-105 nM). Also inhibits GABA(A) channels. Heteropentamer targets studied are composed of alpha-1-beta-3-gamma-2 (GABRA1-GABRB3-GABRG2) subunits (IC(50)=236 nM), alpha-1-beta-2-gamma-2 (GABRA1-GABRB2-GABRG2) subunits (IC(50)=469 nM), alpha-2-beta-2-gamma-2 (GABRA2-GABRB2-GABRG2)...
TMPH-03036 Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)

Cardiotoxin 2,CTX A2,Cardiotoxin 1A,Cardiotoxin A2,...

Naja atra E. coli
Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities, but 2-fold less important than that of CTX-A4. It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity. It may interact with sulfatides in the cell membrane which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induce mitochondrial swelling and fragmentation.

重组蛋白

Alpha-cobratoxin Protein, Naja kaouthia, Recombinant (GST & His & Myc)
Cat.No: TMPH-03037
Species: Naja kaouthia
Expression System: E. coli
Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)
Cat.No: TMPH-03036
Species: Naja atra
Expression System: E. coli
TargetMol Loading
联系我们
400-820-0310

上海市静安区江场三路238号8楼