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Cat. No.	Product Name	Target	Signaling Pathways
T14178	Alicapistat ABT-957	Others	Others
	Alicapistat (ABT-957) is a human calpains 1 and 2 inhibitor. It can potentially be used to treat Alzheimer's disease (AD).
T60150	(1S,2R)-Alicapistat	Cysteine Protease	Proteases/Proteasome
	(1S,2R)-Alicapistat ((1S,2R)-ABT-957) is a highly efficient, orally active compound that selectively inhibits human calpains 1 and 2, with promising implications for Alzheimer's disease (AD) therapy [1]. This compound effectively addresses the metabolic liability associated with carbonyl reduction, while demonstrating potent inhibition of calpain 1 with an IC50 value of 395 nM [2].