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Cat. No. Product Name Target Signaling Pathways
T83169 Adenylyl cyclase-IN-1

Adenylyl cyclase-IN-1,一种Adenylyl cyclase抑制剂,具有潜在的应用价值于眼部张力减退研究领域。
T60003 AC1-IN-1

Adenylyl cyclase Neuroscience
AC1-IN-11 型腺苷酸环化酶的选择性抑制剂(AC1,IC50 = 0.54 µM)。
T7813 α-MSH

MSH, amide,CZEN-002,美拉诺坦,α-Melanocyte-Stimulating Hormone (MSH), amide

Melanocortin Receptor; Adenylyl cyclase GPCR/G Protein; Neuroscience
α-MSH (MSH, amide) 是一种内源性神经肽,是一种内源性黑皮质素受体 4 (MC4R) 激动剂,具有抗炎和解热活性。
T63893 Adenylyl cyclase type 2 agonist-1

Adenylyl cyclase type 2 agonist-1 是腺苷酸环化酶 2 型 (AC2) 有效的激动剂 (EC50: 90 nM)。Adenylyl cyclase type 2 agonist-1 能够抑制 Interleukin-6 的表达,是一种潜在的对抗呼吸系统疾病的先导化合物。
T83843 2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate sodium

2'(3')-ANT-GTP

2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate(2'-ANT-GTP)及3'-ANT-GTP是荧光GTP衍生物,能够自发进行异构化。2'(3')-ANT-GTP在水中的激发波长为330 nm时,发射最大波长为428 nm。它抑制哺乳动物腺苷酸环化酶1(AC1;在锰存在下Ki=10 nM)、B. anthracis AC毒素水肿因子(在锰和镁存在下Kis分别为4.113 µM)及B. pertussis AC毒素CyaA(在锰存在下Ki=29 µM)。
T36720 Deacetylforskolin

Deacetylforskolin is a diterpene and a derivative of forskolin that has been found inC. forskohliiand has diverse biological activities.1,2,3,4It activates rat adipocyte adenylyl cyclase (IC50= 20 μM) and inhibits glucose transport in rat adipocyte plasma membranes.2Deactylforskolin (30-1,000 μg/kg) reduces blood pressure in spontaneously hypertensive rats.3It also attenuates hypercapnia-induced impairments in the passive avoidance response in mice.4 1.Gabetta, B., Zini, G., and Danieli, B.Minor...

化合物

Adenylyl cyclase-IN-1
Cat.No: T83169
Synonym:
Target:
AC1-IN-1
Cat.No: T60003
Synonym:
Target: Adenylyl cyclase
α-MSH
Cat.No: T7813
Synonym: MSH, amide,CZEN-002,美拉诺坦,α-Melanocyte-Stimulating Hormone (MSH), amide
Target: Melanocortin Receptor, Adenylyl cyclase
Adenylyl cyclase type 2 agonist-1
Cat.No: T63893
Synonym:
Target:
2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate sodium
Cat.No: T83843
Synonym: 2'(3')-ANT-GTP
Target:
Deacetylforskolin
Cat.No: T36720
Synonym:
Target:
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