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Search Results for " acyl carrier protein "

10

抑制剂 & 化合物

1

天然产物

21

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1837	Acyl Carrier Protein (ACP) (65-74) Acyl Carrier Protein (ACP) 65-74
	Acyl Carrier Protein (ACP) (65-74) is an active acyl carrier protein (ACP) fragment.Acyl Carrier Protein (ACP) is a component of plastid-located plant fatty acid synthetase. It binds acyl groups covalently via the prosthetic group, 4-phosphopantetheine, d
T19642	Nilofabicin CG 0549,CG-0549,CG-400549,CG 400549,CG0549,CG400549	Antibacterial	Microbiology/Virology
	Nilofabicin (CG-400549) 是一种有效的烯酰-(酰基-载体-蛋白)还原酶下降(FabI)抑制剂，可用于治疗复杂急性疾病的研究。
T4105	AFN-1252 Debio 1452,API-1252	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	AFN-1252 (Debio 1452)是一种FabI 的高效抑制剂，能抑制金黄色葡萄球菌。
T28732	SCH-538415	Others	Others
	SCH-538415 is an inhibitor of acyl carrier protein synthase from a microorganism. SCH-538415 exhibited inhibitory activity in the acyl carrier protein synthase (AcpS) assay with an IC(50) value of 4.19 microM and showed antibacterial activity against Stap
T70499	Afabicin diolamine	Others	Others
	Afabicin (formerly Debio 1450, AFN-1720) is a prodrug of afabicin desphosphono, an enoyl-acyl carrier protein reductase (FabI) inhibitor, and is a first-in-class antibiotic with a novel mode of action to specifically target fatty acid synthesis in Staphylococcus spp.
T37070	Pyridomycin	Others	Others
	Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 μg/ml).
T73032	MtInhA-IN-1	Others	Others
	MtInhA-IN-1是一种口服活性的选择性结核分枝杆菌NADH依赖性烯酰基载体蛋白还原酶(MtInhA)抑制剂，IC50值为0.23 μM。对结核分枝杆菌H37Rv菌株，其MIC为0.4 μM。
T60643	FabH-IN-1	Others	Others
	FabH-IN-1 (化合物 3f) 可有效对抗革兰氏阳性菌和革兰氏阴性菌，并且也是一种良好的抗氧化剂。FabH-IN-1 是细菌FabH 酶的抑制剂，该酶是一种广谱抗菌靶标。
T73918	Lauroyl coenzyme A lithium	Others	Others
	Lauroyl coenzyme A lithium salt 是一种辅酶 A。辅酶 A 作为酰基载体，即乙酰辅酶 A。十二烷酰辅酶 A (C12-CoA) 是一种长链 (C-12) 饱和脂肪酰辅酶 A，用作脂质代谢的中间体，参与脂质生物合成和脂肪酸转运。月桂酰辅酶 A 是底物用于 FAM34A 蛋白和萤火虫荧光素酶的产物。
T35634	Platensimycin	Others	Others
	Platensimycin (PTM) is an antibiotic produced by S. platensis that inhibits Gram-positve bacteria by selectively inhibiting cellular lipid biosynthesis (IC50 = 0.1 μM). It targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s = 48 and 160 nM for S. aureus and E. coli enzymes, respectively). By specifically targeting fatty acid synthesis in bacteria, PTM is thought to be a promising agent for overcoming antibiotic ...

化合物

Acyl Carrier Protein (ACP) (65-74)

Cat.No: TP1837

Synonym: Acyl Carrier Protein (ACP) 65-74

Cat.No: T19642

Synonym: CG 0549,CG-0549,CG-400549,CG 400549,CG0549,CG400549

Target: Antibacterial

Cat.No: T4105

Synonym: Debio 1452,API-1252

Target: Others, Antibacterial, Antibiotic

Cat.No: T28732

Target: Others

Afabicin diolamine

Cat.No: T70499

Target: Others

Cat.No: T37070

Target: Others

Cat.No: T73032

Target: Others

Cat.No: T60643

Target: Others

Lauroyl coenzyme A lithium

Cat.No: T73918

Target: Others

Cat.No: T35634

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T38069	Aquastatin A	Others	Others
	Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K....

天然产物

Cat.No: T38069

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03524	KAS III Protein, S. aureus, Recombinant (His & Myc) 3-oxoacyl-[acyl-carrier-prote...	Staphylococcus aureus	E. coli
	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. KAS III Protein, S. au...
TMPH-03518	ACP Protein, S. aureus, Recombinant (GST) acpP,Fatty acid synthase acyl carrier ...	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 35.5 kDa and the accession number is P0A001.
TMPH-03520	ACP Protein, S. aureus, Recombinant (His & SUMO) acpP,Cytosolic-activating factor,Fatty acid synthase acy...	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.5 kDa and the accession number is P0A001.
TMPH-00564	FabG Protein, E. coli, Recombinant (His & Myc) Beta-Ketoacyl-acyl carrier pr...	E. coli	E. coli
	Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
TMPH-00572	ACP Protein, E. coli, Recombinant (His & SUMO) acpP,Fatty acid synthase acyl carrier ...	E. coli	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis.
TMPH-03519	ACP Protein, S. aureus, Recombinant (His) Cytosolic-activating factor,Fatty acid synthase acyl	Staphylococcus aureus	P. pastoris (Yeast)
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.5 kDa and the accession number is P0A001.
TMPH-00571	ACP phosphodiesterase Protein, E. coli, Recombinant (His & Myc) yajB,acpH,Acyl carrier protein ph...	E. coli	E. coli
	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
TMPH-03048	LpxA Protein, MenC, Recombinant (His) lpxA,Acyl-[acyl-carrier-prote...	MenB	E. coli
	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
TMPH-00565	FabB Protein, E. coli, Recombinant (His & Myc & SUMO) Beta-ketoacyl-ACP synthase I,3-oxoacyl-[	E. coli	E. coli
	FabB Protein, E. coli, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO and C-Myc tag. The predicted molecular weight is 61.3 kDa and the accession number is P0A953.
TMPH-03564	MCAT Protein, S. aureus, Recombinant (His & SUMO) Malonyl CoA-acyl carrier protein ...	Staphylococcus aureus	E. coli
	MCAT Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q5HGK3.
TMPH-03563	MCAT Protein, S. aureus, Recombinant (His) fabD,Malonyl CoA-acyl carrier protein<...	Staphylococcus aureus	P. pastoris (Yeast)
	MCAT Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 35.6 kDa and the accession number is Q5HGK3.
TMPH-03596	Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) acpS,4'-phosphopantetheinyl transferase AcpS,Holo-[acyl<...	Streptococcus pyogenes	Baculovirus Insect Cells
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 17.1 kDa and the accession number is Q48RM7.
TMPH-03597	Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) 4'-phosphopantetheinyl transferase AcpS,Holo-[acyl-...	Streptococcus pyogenes	E. coli
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.3 kDa and the accession number is Q48RM7.
TMPH-00711	BioH Protein, E. coli, Recombinant (His & Myc) bioB,Carboxylesterase BioH,Biotin synthesis protein...	E. coli	E. coli
	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. E.coli employs a methylation and demethylation strategy to allow elongation of a temporarily disguised malonate moiety to a pimelate moiety by the fatty acid synthetic enzymes. BioH shows a preference for short chain fatty acid esters (acyl c...
TMPH-03536	FabI Protein, S. aureus, Recombinant (His & SUMO) Enoyl-[acyl-carrier-protein] redu...	Staphylococcus aureus	E. coli
	Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism. FabI Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.0 kDa and the accession number is Q6GI75.
TMPH-00017	acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) Holo-ACP synthase,Holo-[acyl-carrier-p...	Acholeplasma laidlawii	E. coli
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.9 kDa and the accession number is A9NHV3.
TMPH-03008	ENR Protein, Mycobacterium tuberculosis, Recombinant (His) FAS-II enoyl-ACP reductase,Enoyl-ACP reductase,Enoyl-[ac...	Mycobacterium tuberculosis	E. coli
	ENR Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.6 kDa and the accession number is P9WGR0.
TMPH-03433	ACB1 Protein, S. cerevisiae, Recombinant (His) Acyl-CoA-binding protein	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. ACB1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 12.1 kDa and the accession number is P31787.
TMPH-02492	DBI Protein, Mouse, Recombinant (His & Myc) Endozepine (EP),Diazepam-binding inhibitor,DBI,Acyl...	Mouse	E. coli
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. DBI Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted ...
TMPH-00890	DBI Protein, Human, Recombinant (aa 2-104, His) Acyl-CoA-binding protein,Diazepam-binding ...	Human	E. coli
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. DBI Protein, Human, Recombinant (aa 2-104, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecul...
TMPH-03235	DBI Protein, Rat, Recombinant (His & Myc) Endozepine (EP),ACBP,DBI,Acyl-CoA-binding prote...	Rat	E. coli
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. DBI Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted mo...

重组蛋白

KAS III Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03524

Species: Staphylococcus aureus

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (GST)

Cat.No: TMPH-03518

Species: Staphylococcus aureus

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03520

Species: Staphylococcus aureus

Expression System: E. coli

FabG Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00564

Species: E. coli

Expression System: E. coli

ACP Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00572

Species: E. coli

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03519

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

ACP phosphodiesterase Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00571

Species: E. coli

Expression System: E. coli

LpxA Protein, MenC, Recombinant (His)

Cat.No: TMPH-03048

Species: MenB

Expression System: E. coli

FabB Protein, E. coli, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-00565

Species: E. coli

Expression System: E. coli

MCAT Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03564

Species: Staphylococcus aureus

Expression System: E. coli

MCAT Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03563

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)

Cat.No: TMPH-03596

Species: Streptococcus pyogenes

Expression System: Baculovirus Insect Cells

Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-03597

Species: Streptococcus pyogenes

Expression System: E. coli

BioH Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00711

Species: E. coli

Expression System: E. coli

FabI Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03536

Species: Staphylococcus aureus

Expression System: E. coli

acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc)

Cat.No: TMPH-00017

Species: Acholeplasma laidlawii

Expression System: E. coli

ENR Protein, Mycobacterium tuberculosis, Recombinant (His)

Cat.No: TMPH-03008

Species: Mycobacterium tuberculosis

Expression System: E. coli

ACB1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03433

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

DBI Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02492

Species: Mouse

Expression System: E. coli

DBI Protein, Human, Recombinant (aa 2-104, His)

Cat.No: TMPH-00890

Species: Human

Expression System: E. coli

DBI Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03235

Species: Rat

Expression System: E. coli

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