Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3338 |
Ceralasertib
AZD6738 |
ATM/ATR | DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
Ceralasertib (AZD6738) 是一种具有口服活性的选择性 ATR 激酶抑制剂,IC50 为 1 nM。 | |||
T26981 |
Ceralasertib formate
Ceralasertib,AZD-6738,AZD 6738,AZD6738 |
||
Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR- | |||
T12795 |
(S)-Ceralasertib
(S)-AZD6738 |
Others | Others |
(S)-Ceralasertib is a potent and selective inhibitor of sulfoximine morpholinopyrimidine ATR with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics. . |