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Cat. No. Product Name Target Signaling Pathways
T9023 Atuliflapon

AZD5718

FLAP Immunology/Inflammation
Atuliflapon (AZD5718) 是可口服的FLAP(5 -脂氧合酶激活蛋白)的抑制剂,IC50值为 2 nM,可用于冠状动脉疾病的研究。
T69969 RWJ-60475

RWJ-60475 is a novel CD45 phosphatase inhibitor.
T69970 AZD5718

AZD5718 is a potent and selective FLAP inhibitor (IC50 = 2.0 nM) for Treatment of Coronary Artery Disease. AZD5718 demonstrated a dose dependent and greater than 90% suppression of leukotriene production over 24 h. Preclinical toxicology studies in rat and dog did not show any serious adverse events of clinical significance. Currently, AZD5718 is evaluated in a phase 2a study for treatment of coronary artery disease.

化合物

Atuliflapon
Cat.No: T9023
Synonym: AZD5718
Target: FLAP
RWJ-60475
Cat.No: T69969
Synonym:
Target:
AZD5718
Cat.No: T69970
Synonym:
Target:
TargetMol Loading
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