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Targets Recommended: Akt

1

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T36310 AKT-IN-6

INCB-047775

Akt Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
AKT-IN-6 (INCB-047775)对ATK 有抑制作用。Akt 是对生长因子、细胞因子和其他细胞刺激的细胞信号传导的重要组成部分。Akt 的异常激活与2型糖尿病和癌症的发生密切相关。

化合物

AKT-IN-6
Cat.No: T36310
Synonym: INCB-047775
Target: Akt
Cat. No. Product Name Species Expression System
TMPH-02271 BTK Protein, Human, Recombinant (His)

BPK,AGMX1,ATK,B-cell progenitor kinase,Tyrosine-pro...

Human Baculovirus Insect Cells
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in...

重组蛋白

BTK Protein, Human, Recombinant (His)
Cat.No: TMPH-02271
Species: Human
Expression System: Baculovirus Insect Cells
TargetMol Loading
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