Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6764 |
ATI-2341
ATI2341 |
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
ATI-2341 是 C-X-C 趋化因子受体 4 型功能选择性变构激动剂,作为偏向配体有利于 Gα1 激活。它是一种变构激动剂,可激活抑制性异源三聚体 G 蛋白 (Gi) 以促进抑制 cAMP 产生并诱导钙动员。 | |||
T6764L |
ATI-2341 acetate(1337878-62-2 free base)
|
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
ATI-2341 acetate(1337878-62-2 free base) 是一种有效的 CXCR4 变构激动剂,它激活 Gα1 而不是 Gα13。 ATI-2341 acetate 激活抑制性异源三聚体 G 蛋白 (GI) 以促进对 cAMP 产生的抑制并诱导钙动员。 | |||
TP1354 |
ATI-2341 TFA (1337878-62-2 free base)
ATI-2341 TFA |
||
ATI-2341 is an effective functionally selective allosteric agonist for the c-x-c chemokine receptor type 4 (CXCR4), which ACTS as a biased ligand in favor of G G G G G 1 activation instead of G G G G G 13.ATI-2341 activates the inhibitory heterotrimer G p |