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Cat. No. Product Name Target Signaling Pathways
T1866 AT-56

Others; PGE Synthase Immunology/Inflammation; Others
AT56 是口服有活性的脂钙蛋白型前列腺素 D 合酶 (L-PGDS) 选择性抑制剂,其IC50=95 μM,Ki=75 μM。它能够特异性地抑制L-PGDS 催化的 PGD2介导的嗜睡或疼痛反应。
T61180 GAT564

GAT564 (Compound 15d) is a highly effective allosteric modulator of cannabinoid 1 receptor (CB1R), having EC50 values of 87 nM and 320 nM for cAMP and β-arrestin2, respectively. It significantly enhances the binding of orthosteric ligands to hCB1R. Moreover, GAT564 exhibits remarkable efficacy as a topical agent, resulting in a significant reduction of intraocular pressure (IOP) in an ocular normotensive murine model of glaucoma [1].

化合物

AT-56
Cat.No: T1866
Synonym:
Target: Others, PGE Synthase
GAT564
Cat.No: T61180
Synonym:
Target:
TargetMol Loading
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