Cat. No. | Product Name | Target | Signaling Pathways |
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T64237 |
ASB14780
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ASB14780 是一种 4-苯氧衍生物,是一种胞质磷脂酶 cPLA2α 抑制剂 (IC50: 20 nM)。 | |||
T37842 |
ASB 14780
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Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor (IC50 = 20 nM). Selective for cPLA2α over secreted PLA2α (sPLA2α; exhibits no inhibition at 10 μM). Inhibits cPLA2α-dependent inflammatory responses in vitro in guinea pig and human whole-blood assays. Improves diet-induced liver injury and CCl4-induced hepatic fibrosis in vivo. Orally bioavailable. |