Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39695 |
ARD-2128
|
Androgen Receptor | Endocrinology/Hormones |
ARD-2128 是高效的雄激素受体降解剂 PROTAC。它可有效降低 雄激素受体蛋白并抑制肿瘤组织中雄激素受体调节的基因,在没有毒性迹象的情况下抑制肿瘤生长。它有用于前列腺癌研究的价值。 | |||
T24411 |
Y08060
Y 08060,Y-08060 |
||
Y08060 is an effective and selective BET Inhibitor for the Treatment of Prostate Cancer. Y08060 effectively suppresses cell growth, colony formation, and expression of androgen receptor (AR), AR regulated genes, and MYC in prostate cancer cell lines. Y08060 has IC50 values of 3.23 and 4.41 μM in inhibition of cell viability in the C4 2B and LNCaP cell lines, respectively. | |||
T30123 |
ARD-69
|
||
ARD-69 is a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer. ARD-69 induces degradation of AR protein in AR-positive prostate cancer cell lines in a dose- and time-dependent mann |