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Cat. No. Product Name Target Signaling Pathways
T10358 Netarsudil Dihydrochloride

AR-13324 Dihydrochloride

ROCK Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) 是 Rho 相关蛋白激酶 (ROCK) 和去甲肾上腺素转运蛋白 (NET) 的抑制剂,可有效降低眼压 (IOP)。
T10358L AR-13324 M1 metabolite

Others Others
AR-13324 M1 metabolite is a hydrolysis metabolite of AR-13324 mesylate.
T10357 AR-13324 analog mesylate

Others Others
AR-13324 analog mesylate is an inhibitor of Rho-kinase and a norepinephrine transporter and reduces intraocular pressure in normotensive monkey eyes.
T10358L2 Netarsudil mesylate

AR-13324 (mesylate)

Others Others
Netarsudil mesylate is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.
T71118 NEP-28

NEP-28 is an AR agonist. NEP28 is a new SARM exhibiting high selectivity for androgen receptor. NEP28 showed tissue-selective effect equivalent to or higher than existing SARMs. In addition, the administration of NEP28 increased the activity of neprilysin, a known Aβ-degrading enzyme.

化合物

Netarsudil Dihydrochloride
Cat.No: T10358
Synonym: AR-13324 Dihydrochloride
Target: ROCK
AR-13324 M1 metabolite
Cat.No: T10358L
Synonym:
Target: Others
AR-13324 analog mesylate
Cat.No: T10357
Synonym:
Target: Others
Netarsudil mesylate
Cat.No: T10358L2
Synonym: AR-13324 (mesylate)
Target: Others
NEP-28
Cat.No: T71118
Synonym:
Target:
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