Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TQ0032 |
Rosiptor
洛司普托,AQX-1125 |
Phosphatase | Metabolism |
Rosiptor (AQX-1125) 是一种选择性,具有口服活性的磷酸酶 SHIP1激活剂。它在体外抑制 Akt 磷酸化、炎症介质生成和白细胞趋化,具有抗炎作用。 | |||
TQ0032L |
Rosiptor acetate
AQX-1125,AQX 1125,AQX1125,AQX-1125 acetate |
||
Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast cells and inhibits human leukocyte |