Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T72910 |
APOBEC3G-IN-1
|
Others | Others |
APOBEC3G-IN-1 (MN136.0185) 是一种靶向 APOBEC3G 抑制剂,具有抗 HIV 活性,可用于研究传染病和癌症。 | |||
T9212 |
IMB-301
|
Others; HIV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
IMB-301是根据 hA3G 模型通过虚拟筛选的一种小分子抑制剂。 | |||
T24935 |
Vif-A3G Inhibitor N.41
Vif-A3G Inhibitor-N.41 |
||
Vif-A3G Inhibitor N.41 is a HIV-1 inhibitor-targeting drug. It causes Vif-dependent degradation of human APOBEC3G, thereby inhibiting the Vif-A3G interaction. | |||
T60800 |
Deaminase inhibitor-1
|
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Deaminase inhibitor-1 是一种 APOBEC3G DNA 脱氨酶的抑制剂,IC50值为 18.9 μM。 | |||
T60342 |
HIV-1 inhibitor-47
|
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HIV-1 inhibitor-47 is a compound that effectively inhibits HIV-1 by preventing the vif-dependent degradation of human APOBEC3G. It has a notable inhibition effect, with an IC50 value of 14.33 μM. Additionally, HIV-1 inhibitor-47 is involved in the synthesis of derivatives of 1-(2-pyrimidinyl)piperazine, which have the potential to exhibit antianxiety, antidepressant, and antipsychotic effects [1] [2] [3]. |