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Cat. No. Product Name Target Signaling Pathways
T61051 ANO1-IN-1

Chloride channel Membrane transporter/Ion channel
ANO1-IN-1是一种选择性的 ANO1 通道阻断剂,对 ANO1ANO2有抑制作用, IC50 值分别为 2.56 μM 和 15.43 μM。ANO1-IN-1 对胶质瘤细胞的增殖抑制作用显著。
T60846 ANO1-IN-3

ANO1-IN-3 (Compound 3n) 可诱导细胞凋亡,是ANO1 的选择性抑制剂,IC50值为 1.23 μM。
T61608 ANO1-IN-2

ANO1-IN-2 (Compound 10q) is a potent and selective ANO1 channel blocker. It exhibits an IC50 value of 1.75 μM against ANO1 and 7.43 μM against ANO2. Furthermore, ANO1-IN-2 demonstrates significant anti-proliferative activity in glioblastoma cells [1].
T61818 DFBTA

DFBTA is a highly effective and orally active inhibitor of ANO1, specifically the calcium-activated chloride channel anoctamin-1. It exhibits potent inhibitory activity, with an IC 50 of 24 nM. Notably, DFBTA demonstrates significant analgesic efficacy in treating inflammatory pain [1].

化合物

ANO1-IN-1
Cat.No: T61051
Synonym:
Target: Chloride channel
ANO1-IN-3
Cat.No: T60846
Synonym:
Target:
ANO1-IN-2
Cat.No: T61608
Synonym:
Target:
DFBTA
Cat.No: T61818
Synonym:
Target:
TargetMol Loading
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