Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14216 |
AMG 837
|
Others | Others |
AMG 837 was found to be a partial agonist on GPR40 with maximal activity 85% of that shown by DHA under our standard assay conditions. Overall, AMG 837 was both highly potent and selective in vitro. AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a sup | |||
T12655 |
(Rac)-AMG8379
(Rac)-AMG8380 |
Sodium Channel | Membrane transporter/Ion channel |
(Rac)-AMG8379 ((Rac)-AMG8380) 是 AMG8379 的外消旋体,是一种具有口服活性和选择性的磺胺 NaV1.7 拮抗剂。 |