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Cat. No. Product Name Target Signaling Pathways
T10298L AMG-548

p38 MAPK MAPK
AMG-548 is an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ and is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50=3 nM
T10298 AMG-548 hydrochloride (864249-60-5 free base)

AMG-548 hydrochloride

p38 MAPK MAPK
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50: 3 nM).
T10298L2 AMG-548 dihydrochloride (864249-60-5 free base)

AMG-548 dihydrochloride

p38 MAPK MAPK
AMG-548 dihydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhibition of whole blood LPS stimulate

化合物

AMG-548
Cat.No: T10298L
Synonym:
Target: p38 MAPK
AMG-548 hydrochloride (864249-60-5 free base)
Cat.No: T10298
Synonym: AMG-548 hydrochloride
Target: p38 MAPK
AMG-548 dihydrochloride (864249-60-5 free base)
Cat.No: T10298L2
Synonym: AMG-548 dihydrochloride
Target: p38 MAPK
TargetMol Loading
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