Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38933 |
HKYellow-AM (6/12-mixture)
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HKYellow-AM (6/12-mixture) is a fluorogenic probe, which can be used for sensitive and specific detection of peroxynitrite. | |||
T13546 |
AM12
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TRP/TRPV Channel | Membrane transporter/Ion channel |
AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM). | |||
TP1880L1 |
PAMP-12 (human, porcine) acetate
PAMP-12 (human, porcine) acetate(196305-05-2 free base) |
Others | Others |
PAMP-12 (human, porcine) acetate (PAMP-12 (human, porcine) acetate (196305-05-2 free base)) 是 ir-PAMP 的主要成分,由 AM 前体加工而成,PAMP-20 也是如此,并且可能参与心血管控制。 | |||
T29941 |
AM-6826
AM 6826 |
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AM-6826 is a Pan-Pim inhibitor. In a mouse xenograft tumor model, AM-6826 can inhibit the growth of KMS-12-BM melanoma by 93%. | |||
TP2214 |
Adrenomedullin (1-12), human
|
Others | Others |
Adrenomedullin (AM) (1-12), human, is a peptide with the sequence Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg. Adrenomedullin (AM) (1-12), human, was initially identified as a vasodilator, and as such, it has the ability to relax vascular tone. Other | |||
T36398 |
Paclitaxel octadecanedioate
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Paclitaxel octadecanedioate is a prodrug form of paclitaxel that is comprised of paclitaxel conjugated to 1,18-octadecanedioic acid.1 Unlike paclitaxel, it does not promote tubulin polymerization in vitro when used at a concentration of 10 μM. A 5:1 mixture of paclitaxel octadecanedioate:human serum albumin (HSA) is cytotoxic to HT-1080, PANC-1, and HT-29 cells (IC50s = 12, 2.48, and 8.62 nM, respectively). This mixture reduces tumor growth and increases survival in an HT-1080 mouse xenograft mo... |