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Cat. No. Product Name Target Signaling Pathways
T62606 ALOX15-IN-2

Lipoxygenase Metabolism
ALOX15-IN-2 是一种有效的 ALOX15 亚油酸加氧酶 (linoleate oxygenase) 活性抑制剂,抑制ALOX15 直系同源物亚油酸 (LA) 和花生四烯酸 (AA)进行氧化作用 , IC50 分别为 1.55 和 2.79 μM。
T37265 15(R)-Lipoxin A4

15(R)-Lipoxin A4,AT-Lipoxin A4

Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspirin-triggered formation of 15(R)-HETE from arachidonic acid. [1] [2] 15(R)-LXA4 inhibits LTB4-induced chemotaxis, adherence, and transmigration of neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.[2] [3] The anti-inflammatory effects of aspirin may...

化合物

ALOX15-IN-2
Cat.No: T62606
Synonym:
Target: Lipoxygenase
15(R)-Lipoxin A4
Cat.No: T37265
Synonym: 15(R)-Lipoxin A4,AT-Lipoxin A4
Target:
TargetMol Loading
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