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Search Results for " aldh1a2 "

5

抑制剂 & 化合物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T39675	ALDH1A2-IN-1 ALDH1A2-IN-1
	ALDH1A2-IN-1 is a reversible inhibitor of the active site of ALDH1A2, showing a significant affinity for the enzyme with an IC50 value of 0.91 μM and a Kd value of 0.26 μM. This compound interacts hydrophobically with the enzyme, contributing to its inhibitory properties.
T7835	CM10 CM 10	Dehydrogenase	Metabolism
	CM10是一种有效的乙醛脱氢酶 1A (ALDH1A) 家族选择性抑制剂，对于 ALDH1A1，ALDH1A2 和 ALDH1A3 的IC50分别为 1700、740 和 640 nM。CM 10 可以调节新陈代谢并具有抗癌活性。
T23533	WIN 18446	Dehydrogenase	Metabolism
	Win 18446 是口服有效的睾丸特异性的ALDH1a2的抑制剂，IC50为 0.3 μM。Win 18446 抑制睾丸内视黄醇合成视黄酸，可逆的抑制多个物种的精子形成，。
T39676	CM121 CM121
	CM121 is a reversible inhibitor of ALDH1A2 that acts specifically on the active site, exhibiting an IC50 of 0.54 μM and a Kd of 1.1 μM. It exerts its inhibitory effect through multiple hydrophobic interactions.
T12196	NCT-505	Dehydrogenase	Metabolism
	NCT-505是乙醛脱氢酶的选择性抑制剂，IC50为 7 nM。对 hALDH1A2，hALDH1A3，hALDH2，hALDH3A1的抑制作用较弱，IC50分别为 >57，22.8，20.1，>57 μM。

化合物

Cat.No: T39675

Synonym: ALDH1A2-IN-1

Cat.No: T7835

Synonym: CM 10

Target: Dehydrogenase

Cat.No: T23533

Target: Dehydrogenase

Cat.No: T39676

Synonym: CM121

Cat.No: T12196

Target: Dehydrogenase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00710	ALDH1A2 Protein, Human, Recombinant (His) RALDH(II),Retinal dehydrogenase 2,RALDH2,<...	Human	E. coli
	Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate norma...
TMPY-01583	ALDH1A1 Protein, Human, Recombinant (His) ALDH11,ALDC,PUMB1,ALDH-E1,HEL-S-53e,HEL-9,...	Human	E. coli
	Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases f...

重组蛋白

ALDH1A2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00710

Species: Human

Expression System: E. coli

ALDH1A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01583

Species: Human

Expression System: E. coli

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