Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7493 |
AG-13958
AG-013958,N-[2-氟-5-[[3-[(1E)-2-(2-吡啶基)乙烯基]-1H-吲唑-6-基]氨基]苯基]-1,3-二甲基-1H-吡唑-5-甲酰胺 |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
AG-13958 (AG-013958) 是 VEGFR 酪氨酸激酶抑制剂,可用于年龄相关性黄斑变性 (AMD) 的脉络膜新生血管形成的研究。 | |||
T69452 |
AG-13958 monohydrochloride
|
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AG-13958 monohydrochloride is the HCl salt of AG-13958 --- a VEGFA inhibitor potentially for the treatment of age-related macular degeneration. Neovascular AMD, a subtype characterized by the growth of new, pathologic blood vessels, results in most of the cases of severe and rapid vision loss associated with AMD. A critical activator of angiogenesis in neovascular AMD is VEGF. |