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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76860 Bimagrumab

Bimagrumab (Anti-ACVR2B Reference Antibody) 是一种人单克隆抗体,可阻断激活素 II 型受体 (ActRII),对ActRIIB 和ActRIIA 的KD 值分别为 1.7 pM 和 434 pM。Bimagrumab 可用于病理性肌肉损失和无力的研究。

化合物

Bimagrumab
Cat.No: T76860
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01447 ACVR2A Protein, Mouse, Recombinant (His)

ActrIIa,activin A receptor, type IIA,Acvr2,TactrII

Mouse HEK293 Cells
ACVR2A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is A2AI38.
TMPY-01602 ACVR2A Protein, Mouse, Recombinant (His & hFc)

Acvr2,activin A receptor, type IIA,ActrIIa,TactrII

Mouse HEK293 Cells
ACVR2A Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 41.4 kDa and the accession number is A2AI38.
TMPJ-00315 ACVR2A Protein, Human, Recombinant (hFc & His)

ACTR-IIA,Activin Receptor Type IIA,ACTRIIA,Activin ...

Human HEK293 Cells
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors....

重组蛋白

ACVR2A Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01447
Species: Mouse
Expression System: HEK293 Cells
ACVR2A Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-01602
Species: Mouse
Expression System: HEK293 Cells
ACVR2A Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00315
Species: Human
Expression System: HEK293 Cells
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