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Cat. No.	Product Name	Target	Signaling Pathways
T5381	A-893
	A-893 是一个具有细胞活性的，甲基转移酶SMYD2的抑制剂，IC50值为 2.8 nM。
T68893	Vanoxerine free base
	Vanoxerine, also known as GBR-12909; I-893, is a dopamine ruptake inhibitor potentially for the treatment of atrial fibrillation.
T82227	HDAC1/CDK7-IN-1	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	HDAC1/CDK7-IN-1（compound 8e）是一款针对CDK7和HDAC1的双重抑制剂，其IC50值分别为893 nM 和248 nM 。该化合物能有效抑制MDA-MB-231、MCF-7、A549及HCT-116等多种癌细胞系的生长。此外，HDAC1/CDK7-IN-1在HCT-116细胞中诱发了细胞周期阻滞与凋亡（apoptosis）现象，并能够抑制其细胞迁移能力。
T36807	Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)
	Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 ...