Cat. No. | Product Name | Target | Signaling Pathways |
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T28882 |
Sultosilic acid, piperazine salt
A-585,Mimedran,piperazine-sultosylate,A585,A 585 |
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Sultosilic acid piperazine salt is a drug with lowering lipid activity. It causes significant shortening of the euglobulin lysis time and a significant diminution of platelet adhesiveness, as well as statistically significant decrease of triglycerides, to | |||
T15609 |
JC-1
CBIC2 |
Others | Others |
JC-1 (CBIC2) 是一种荧光亲脂性羰花青染料,用于测量线粒体膜电位。线粒体膜电位较高时,它在基质中汇聚形成聚合物,可以产生红色荧光(λex=585 nm,λem=590 nm)。线粒体膜电位较低时,它不能聚集在线粒体基质中,以单体形式存在产生绿色荧光(λex=510 nm,λem=527 nm)。 | |||
T124605 |
Neotrehalose
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Neotrehalose 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124605,CAS号为 585-91-1。 | |||
T69915 |
GX-585
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GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2. | |||
T41152 |
R-BC154
R-BC154 |
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R-BC154 is a high affinity fluorescent α4β1/α9β1 inhibitor (Kdvalues are 12.7 and 38 nM, respectively); fluorescent version of BOP. Rapidly and preferentially mobilizes HSCs and progenitorsin vivo. Excitation maximum, 561 nm; emissiosn maximum, 585 nm. | |||
T66804 |
1-(m-Tolyl)ethanone
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1-(m-Tolyl)ethanone 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66804,CAS号为 585-74-0。 | |||
T67472 |
3-(3-(Trifluoromethyl)phenyl)propanoic acid
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3-(3-(Trifluoromethyl)phenyl)propanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67472,CAS号为 585-50-2。 | |||
T37788 |
Resorufin benzyl ether
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Resorufin benzyl ether is a fluorometric probe that acts as a substrate for cytochrome P450 (CYP)3A4. It is typically used near its apparent Km value of 30 μM to screen the inhibition/activation potential of test compounds, to predict potential drug-drug interactions, or to monitor other CYP450 activities. Upon enzyme cleavage, resorufin benzyl ether generates a red fluorescent product (ex. 571 nm/em. 585 nm). | |||
T37388 |
Afizagabar
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Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy[1]. Afizagabar (S44819) is a competitive α5-GABAAR antagonist (Kb=221 nM). Afizagabar selectively inhibits extrasynaptic α5-GABAARs of mouse CA1 pyramidal neurons[1]. Afizagabar (1 and 3 mg/kg; i.p.) significantly diminishes t... | |||
T75374 |
BDP 581/591 NHS ester
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BDP 581/591 NHS ester是一款具备长荧光寿命及高双光子激发截面的硼二吡咯亚甲基染料(Ex=585 nm, Em=594 nm)。该化合物不仅适用于荧光偏振分析,还可与活性氧(ROS)作用产生荧光变化。作为NHS酯类衍生物,它能够与蛋白质、多肽等分子的伯胺和仲胺基团结合。储存条件为避光。 | |||
T38005 |
P11149
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P11149 is a competitive, BBB-penetarated weakly, orally active and selective inhibitor of AChE. P11149 exhibits an IC50 of 1.3 μM for rat BChE/AChE. P11149, a Galanthamine derivative, demonstrates central cholinergic activity, behavioral efficacy and safety. P11149 is used in the study for Alzheimer’s disease[1]. P11149 is a GAL analog that is rapidly hydrolyzed in vivo to yield the potent AChE inhibitor, 6-DMG[1].P11149 exhibits greater s.c. bioavailability than p.o. [1].Oral P11149 in mice pr... |