Cat. No. | Product Name | Target | Signaling Pathways |
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T28882 |
Sultosilic acid, piperazine salt
A-585,Mimedran,piperazine-sultosylate,A585,A 585 |
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Sultosilic acid piperazine salt is a drug with lowering lipid activity. It causes significant shortening of the euglobulin lysis time and a significant diminution of platelet adhesiveness, as well as statistically significant decrease of triglycerides, to | |||
T39243 |
Janelia Fluor® 585, SE
JF585, SE,JF585,NHS |
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Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments. | |||
T69915 |
GX-585
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GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2. | |||
T15609 |
JC-1
CBIC2 |
Others | Others |
JC-1 (CBIC2) 是一种荧光亲脂性羰花青染料,用于测量线粒体膜电位。线粒体膜电位较高时,它在基质中汇聚形成聚合物,可以产生红色荧光(λex=585 nm,λem=590 nm)。线粒体膜电位较低时,它不能聚集在线粒体基质中,以单体形式存在产生绿色荧光(λex=510 nm,λem=527 nm)。 | |||
T124605 |
Neotrehalose
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Neotrehalose 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124605,CAS号为 585-91-1。 | |||
T41152 |
R-BC154
R-BC154 |
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R-BC154 is a high affinity fluorescent α4β1/α9β1 inhibitor (Kdvalues are 12.7 and 38 nM, respectively); fluorescent version of BOP. Rapidly and preferentially mobilizes HSCs and progenitorsin vivo. Excitation maximum, 561 nm; emissiosn maximum, 585 nm. | |||
T66804 |
1-(m-Tolyl)ethanone
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1-(m-Tolyl)ethanone 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66804,CAS号为 585-74-0。 | |||
T67472 |
3-(3-(Trifluoromethyl)phenyl)propanoic acid
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3-(3-(Trifluoromethyl)phenyl)propanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67472,CAS号为 585-50-2。 | |||
T37788 |
Resorufin benzyl ether
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Resorufin benzyl ether is a fluorometric probe that acts as a substrate for cytochrome P450 (CYP)3A4. It is typically used near its apparent Km value of 30 μM to screen the inhibition/activation potential of test compounds, to predict potential drug-drug interactions, or to monitor other CYP450 activities. Upon enzyme cleavage, resorufin benzyl ether generates a red fluorescent product (ex. 571 nm/em. 585 nm). | |||
T37388 |
Afizagabar
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Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy[1]. Afizagabar (S44819) is a competitive α5-GABAAR antagonist (Kb=221 nM). Afizagabar selectively inhibits extrasynaptic α5-GABAARs of mouse CA1 pyramidal neurons[1]. Afizagabar (1 and 3 mg/kg; i.p.) significantly diminishes t... | |||
T75374 |
BDP 581/591 NHS ester
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BDP 581/591 NHS ester是一款具备长荧光寿命及高双光子激发截面的硼二吡咯亚甲基染料(Ex=585 nm, Em=594 nm)。该化合物不仅适用于荧光偏振分析,还可与活性氧(ROS)作用产生荧光变化。作为NHS酯类衍生物,它能够与蛋白质、多肽等分子的伯胺和仲胺基团结合。储存条件为避光。 | |||
T38005 |
P11149
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P11149 is a competitive, BBB-penetarated weakly, orally active and selective inhibitor of AChE. P11149 exhibits an IC50 of 1.3 μM for rat BChE/AChE. P11149, a Galanthamine derivative, demonstrates central cholinergic activity, behavioral efficacy and safety. P11149 is used in the study for Alzheimer’s disease[1]. P11149 is a GAL analog that is rapidly hydrolyzed in vivo to yield the potent AChE inhibitor, 6-DMG[1].P11149 exhibits greater s.c. bioavailability than p.o. [1].Oral P11149 in mice pr... |