Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5442 |
A1874
|
Epigenetic Reader Domain; PROTACs | Chromatin/Epigenetic; PROTAC |
A1874 是一种基于 nutlin 的 BRD4 降解 PROTAC,可诱导细胞中的 BRD4 降解,DC50值为 32 nM。它有效抑制许多癌细胞系的增殖。 | |||
TJS1874 |
(+)-Lycoctonine
牛扁碱 |
||
Compound TJS1874 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 TJS1874,CAS号为 26000-17-9。 | |||
TP1874 |
Alisporivir intermediate-1
|
||
Alisporivir intermediate-1 is a crucial intermediate compound utilized in the synthesis process of Alisporivir, a therapeutic agent employed for the treatment of inflammatory and viral ailments. | |||
T71624 | GB1874 | ||
GB1874 inhibitor of the Wnt pathway that targets the β-cat-TCF4 PPI. GB1874 also affected the proliferation and stemness of Wnt-addicted colorectal cancer (CRC) cells in vitro. Encouragingly, GB1874 inhibited the growth of CRC tumor xenografts in vivo, thus demonstrating its potential for further development into therapeutics against Wnt-associated cancer indications. | |||
T82422 |
F1874-108
|
||
F1874-108是一种油菜素内酯生物合成及信号传导途径的抑制剂。 |