Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16523L |
PhiKan 083
|
Mdm2 | Apoptosis |
PhiKan 083 是咔唑衍生物,可以稳定p53的突变体Y220C,Kd 值为 167 μM。它可用于癌症研究。 | |||
T16523 |
PhiKan 083 hydrochloride
|
Others | Others |
PhiKan 083 hydrochloride is a carbazole derivative. Which binds to the surface cavity and stabilizes Y220C (Kd: 167 μM). It also a relative binding affinity (Kd) of 150 μM in Ln229 cells. |