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Cat. No. Product Name Target Signaling Pathways
T11837 Leptomycin A

CRM1 Membrane transporter/Ion channel
Leptomycin A, a metabolite derived from Streptomyces, acts as an inhibitor of CRM1 (exportin 1) and effectively suppresses HIV-1 replication. Compared to Leptomycin B, it exhibits lesser potency. Leptomycin A hampers the interaction between CRM1 and nuclear export signals, effectively hindering the nuclear export of a wide array of proteins.

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Leptomycin A
Cat.No: T11837
Synonym:
Target: CRM1
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