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Cat. No. Product Name Target Signaling Pathways
T38087 20-hydroxy Leukotriene B4

20-hydroxy Leukotriene B4

20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki = 13.3 nM). However, 20-hydroxy LTB4 is as active as LTB4 in contracting parenchymal strips from guinea pig lung. 20-hydroxy LTB4 retains considerable ligand binding affinity at the BLT2...

化合物

20-hydroxy Leukotriene B4
Cat.No: T38087
Synonym: 20-hydroxy Leukotriene B4
Target:
TargetMol Loading
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