Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3147 | 6',7'-Dihydroxybergamottin | P450 | Metabolism |
6',7'-Dihydroxybergamottin(DHB), a well-known inhibitor of CYP3A4, the inhibition of CYP3A4 activity by DHB includes the inhibition of POR activity, DHB can inhibit nifedipine oxidation in a concentration-dependent manner. | |||
TN3146 |
6',7'-Dihydroxybergamottin acetonide
|
Others | Others |
6',7'-Dihydroxybergamottin is a potent inhibitor of CYP3A activity, and may be primarily responsible for the effects of grapefruit juice on cytochrome P450 activity in humans. |