Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11396 |
GGTI-2418
|
Transferase | Metabolism |
GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regression of breast tumors. GGTI-2418 is a highly potent, competitive, and selective geranylgeranyltransferase I (GGTase I) inhibitor. |