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抑制剂 & 化合物

14

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9574 PF-07304814

Lufotrelvir,卢夫特韦

Lufotrelvir (PF-07304814) 是 PF-00835231 的磷酸盐前药,是一种有效的3CLpro 蛋白酶 (Mpro) 抑制剂,具有 抗SARS-CoV-2 病毒活性。Lufotrelvir 结合并抑制 SARS-CoV-2 3CLpro 活性,Ki 为 174nM。Lufotrelvir 是一种很有前途的单一抗病毒试剂,也可用于与针对冠状病毒生命周期其他关键阶段的其他抗病毒试剂的联合研究。

化合物

PF-07304814
Cat.No: T9574
Synonym: Lufotrelvir,卢夫特韦
Target:
Cat. No. Product Name Species Expression System
TMPK-01344 3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant

M Proteinase,Mpro,3CL-Mpro

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.5kDa and the accession number is YP_009725301.1.
TMPK-01342 3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant

Mpro,3CL-Mpro,3...

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.8kDa and the accession number is YP_009725301.1.
TMPK-01347 3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant

3CL-Mpro,3CL Pr...

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.4kDa and the accession number is YP_009725301.1.
TMPK-01335 3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant

M Proteinase,Mpro,3CL Protease,

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.80 kDa and the accession number is YP_009725301.1.
TMPK-01343 3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant

3CL-Mpro,M Proteinase,Mpro

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.
TMPK-01346 3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant

3CL-Mpro,Mpro,M Proteina...

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8kDa and the accession number is YP_009725301.1.
TMPK-01339 3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant

3CL-Mpro,M Proteinase,3<...

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.78 kDa and the accession number is YP_009725301.1.
TMPK-01336 3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant

3CL-Mpro,3CL Pr...

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.80 kDa and the accession number is YP_009725301.1.
TMPK-01348 3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306)

COVID-19,3CL Protease,M Proteinase,3

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306) is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.
TMPK-01337 3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant

Mpro,3CL-Mpro,3...

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.79 kDa and the accession number is YP_009725301.1.
TMPK-01341 3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant

3CL Protease,3CL-Mpr...

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.
TMPK-01345 3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant

3CL-Mpro,Mpro,M Proteina...

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.5 kDa and the accession number is YP_009725301.1.
TMPK-01338 3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant

M Proteinase,3CL-Mpro,Mpro

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.82 kDa and the accession number is YP_009725301.1.
TMPK-01340 3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant

3CL-Mpro,3CL Pr...

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.72 kDa and the accession number is YP_009725301.1.

重组蛋白

3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant
Cat.No: TMPK-01344
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant
Cat.No: TMPK-01342
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant
Cat.No: TMPK-01347
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant
Cat.No: TMPK-01335
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant
Cat.No: TMPK-01343
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant
Cat.No: TMPK-01346
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant
Cat.No: TMPK-01339
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant
Cat.No: TMPK-01336
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306)
Cat.No: TMPK-01348
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant
Cat.No: TMPK-01337
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant
Cat.No: TMPK-01341
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant
Cat.No: TMPK-01345
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant
Cat.No: TMPK-01338
Species: SARS-CoV-2
Expression System: E. coli
3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant
Cat.No: TMPK-01340
Species: SARS-CoV-2
Expression System: E. coli
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