Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN4245 | Icariside D2 | Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 uM, it induces apoptosis via alteration of expression of apoptosis-related proteins and decreased phosphorylation of AKT in HL-60 cells. |