Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP2074 |
BigLEN(rat)
BigLEN (rat) |
||
Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells. | |||
TP2073L |
BigLEN (mouse) acetate
BigLEN (mouse) acetate (501036-69-7 Free base) |
GPR | Endocrinology/Hormones; GPCR/G Protein |
BigLEN (mouse) acetate 是一种有效的、选择性的孤儿 G 蛋白偶联受体 171 (GPR171) 激动剂,Kd 为 ~0.5 nM。 | |||
TP2073 |
BigLEN(mouse)
BigLEN (mouse) |
||
GPR171 agonist. ProSAAS-derived neuropeptide. Regulates food intake in mice. Inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins. |