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抑制剂 & 化合物

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天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP1174	Endothelin-2 (49-69), human Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine),人内皮素2	Others	Others
	Endothelin-2 (49-69), human (Human endothelin-2) 是一种由 21 个氨基酸组成的血管活性肽。它可与 G 蛋白连接的跨膜受体，ET-RA 和ET-RB 结合。
TP1798	Pep-1 (uncapped) Pep-1 uncapped	Others	Others
	Pep-1 (uncapped) 是一种能够透过细胞的多肽。
T9417L	gamma-preprotachykinin amide (72-92) acetate gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)	Others	Others
	gamma-preprotachykinin amide (72-92) acetate 是一种 21 个氨基酸的肽，属于速激肽 (TK) 家族，在其 C 末端序列中包括神经激肽 A (NKA)。它对中枢 NK-2 受体的亲和力高于 NKA；它对 NK-1 受体的亲和力较低，但是，它有效地刺激唾液分泌，这是由 NK-1 受体激活介导的。
TP1153L	Fibronectin Adhesion-promoting Peptide acetate Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate	Others	Others
	Fibronectin Adhesion-promoting Peptide acetate (Heparin Binding Peptide acetate)(125720-21-0 free base) 是在纤连蛋白的羧基末端肝素结合结构域中发现的肝素结合氨基酸序列之一。
TP2143	Endothelin-2 (49-69), human TFA Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA	Others	Others
	Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.
T38785	Histone H3 (21-44) Histone H3 (21-44)
	Histone H3 (21-44), derived from a sequence of 21-44 amino acids of histone H3, is commonly employed as a substrate, particularly for protein arginine methyltransferase assays, where methylation activity is being examined.
TP1175	Endothelin-3, human, mouse, rabbit, rat Endothelin 3 (Rat,Human)
	Endothelin-3, human, mouse, rabbit, rat , is a cyclic 21 amino acid peptide. It is an endogenous neuropeptide and potent vasoconstrictor.
T81885	Mad1 (6-21) (TFA)
	Mad1 (6-21) TFA，作为Mad1蛋白的6-21片段，与哺乳动物Sin3A PAH2结合，其Kd约为29 nM。
TP1173	Endothelin 3 (Rat,Human) (TFA) Endothelin-3, human, mouse, rabbit, rat TFA
	Endothelin-3, human, mouse, rabbit, rat TFA is a 21-amino acid vasoactive peptide that specifically interacts with G-protein-linked transmembrane receptors, ET-RA and ET-RB.
T40993	Histone H3 (1-21) Histone H3 (1-21)
	Histone H3 (1-21) is a truncated form of the Histone H3 protein consisting of amino acids 1 to 21. It serves as a common substrate for methyltransferase assays targeting Histone 3 at lysine 4 and lysine 9, as well as for acetyltransferase assays targeting Histone 3 at lysine 9 and lysine 14.
T66823	2-Amino-4-(ethylthio)butanoic acid
	2-Amino-4-(ethylthio)butanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66823，CAS号为 67-21-0。
TP1782	CEF3
	CEF3 (SIIPSGPLK) is a peptide representing amino acids 13-21 of the M1 protein in the influenza A virus. The M1 protein is a versatile component of the influenza A virus, carrying out crucial structural and functional tasks throughout the virus's life cycle.
T83193	Acetyl-Heme-Binding Protein 1 (1-21) (human)
	Acetyl-Heme-Binding Protein 1 (1-21) (human)为一种由Acetyl-Heme-Binding Protein 1前21个氨基酸组成的短肽。该肽具有与血红素结合的能力，参与血红素代谢及血红蛋白释放过程。
T82484	ELAAWCRWGFLLALLPPGIAG TFA
	ELAAWCRWGFLLALLPPGIAG TFA (P5) 是由大鼠HER2/neu蛋白衍生的21个氨基酸长的肽段（氨基酸序号5至25）。该化合物在携带HER2阳性肿瘤的小鼠模型中，能够诱发细胞毒性T淋巴细胞(CTL)的反应。
T82485	ELAAWCRWGFLLALLPPGIAG
	ELAAWCRWGFLLALLPPGIAG (P5) 是源自大鼠HER2/neu蛋白的21个氨基酸长肽（氨基酸5-25）。此肽可诱导携带HER2阳性肿瘤小鼠中的细胞毒性T淋巴细胞（CTL）反应。
T82847	BNP (1-21), Pro (Human)
	BNP (1-21), Pro (Human) 是一种由21个氨基酸组成的心脏激素多肽。作为B型利钠肽(BNP)的一部分，与心房利钠肽高度同源，共同构成了心脏的双利钠肽系统。BNP 主要参与心脏发生的调节，并涉及向子宫外环境过渡的生理进程。
T36576	Histone H3 (21-44)-GK-biotin (trifluoroacetate salt) Histone H3 (21-44)-GK-biotin (trifluoroacetate salt)
	Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences and is biotinylated via a C-terminal GK linker. Histone H3 (21-44) contains a lysine residue at position 23 that is subject to acetylation, an arginine at position 26 subject to methylation, and a serine at position 28 subject to phosphorylation, as well as lysine residues at positions 27 and 36 that are subject to methylation and acetylation....
T73651	Forigerimod TFA
	Forigerimod TFA (IPP-201101 TFA) 为 CD4T 细胞调节剂，属于 U1 小核核糖核蛋白 70 kDa 的 21 个氨基酸片段，并在 Ser140 位点磷酸化。它能有效抑制自噬，适用于系统性红斑狼疮 (SLE) 等自身免疫性疾病的研究。
T75878	Catestatin TFA
	Catestatin TFA，一个含有21个氨基酸残基、阳离子性疏水性肽，作为内源性肽，调节心脏功能及血压。它通过烟碱型乙酰胆碱受体(nAChRs)以非竞争性方式抑制儿茶酚胺释放，功能为烟碱类拮抗剂。
T38077	TLQP-21 TFA
	TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions[1][2]. TLQP-21 TFA is a peptide of 21 amino acids. At a dose of 3 μM TLQP-21 induces up to ~69% of th...
T36979	Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt) Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)
	Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence and is biotinylated via a C-terminal GK linker. Unlike histone H3.1 and H3.2, the histone H3.3 variant contains a serine residue at position 31 that is phosphorylated during late prometaphase and metaphase of mitosis. Histone H3 (21-44) also contains lysine residues at positions 23, 27, and 36 that are subject to methylation and acetylation, all of whi...
T9427	Selenocysteine	Others	Others
	Selenocysteine 被认为是核糖体介导的蛋白质合成中的第 21 个氨基酸，其特异性掺入由 UGA 密码子指导。
T73650	Forigerimod
	Forigerimod (IPP-201101) 是一种 CD4T 细胞调节剂。Forigerimod 是 U1 小核核糖核蛋白 70 kDa 的 21 个氨基酸片段，在 Ser140 位点被磷酸化。Forigerimod 可以有效抑制自噬。Forigerimod 可用于系统性红斑狼疮 (SLE) 等自身免疫性疾病的研究。
T35918	N-Arachidonoyl Taurine
	N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretio...
T83742	SBP1 TFA Spike Binding Peptide 1
	Spike binding peptide 1 (SBP1) 为对应于血管紧张素转换酶2 (ACE2) 的第21至43位氨基酸的肽。已将脂质纳米粒子 (LNPs) 包裹的抗病毒化合物奥司他韦磷酸盐与SBP1结合并通过体外研究评估其控制释放奥司他韦磷酸盐的长期潜力。SBP1 (2%) 固定于交联的羟基丙烯酸酯和乙基黄原酸乙酯网络，提高了对严重急性呼吸系统冠状病毒2(SARS-CoV-2)刺突糖蛋白，亦称表面糖蛋白，的网络捕获效率。
T36673	CC 401 dihydrochloride
	High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of active, phosphorylated JNK. Exhibits > 40-fold selectivity for JNK over p38, ERK, IKK2, protein kinase C, Lck and ZAP70. Hepatoprotective. Also inhibits HCMV replication. Uehara et al (2004) c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation. Transplantation. 78 324 PMID:15316358 \|Uehara et al (2005) JNK mediates hepatic ischemia reperfusion injury. J...
T36695	TAS-103
	TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research. TAS-103 is a dual inhibitor of DNA topoisomerase I/II. TAS-103 (0.1-10 μM) is active on CCRF-CEM cells, with an IC50 value of 5 nM. TAS-103 (0.1 μM) significantly increases levels of topo IIα FITC immunofluorescence in individual CCRF-CEM cells[1]. TAS-103 (0.01-1 μM) is highly cytotoxic to Lewis lung carcinoma (LLC) cells, and Liposomal TAS-103 is almost as active as free TAS-103[2]. TAS-103 inhibits the viability ...

化合物

Endothelin-2 (49-69), human

Cat.No: TP1174

Synonym: Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine),人内皮素2

Target: Others

Pep-1 (uncapped)

Cat.No: TP1798

Synonym: Pep-1 uncapped

Target: Others

gamma-preprotachykinin amide (72-92) acetate

Cat.No: T9417L

Synonym: gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)

Target: Others

Fibronectin Adhesion-promoting Peptide acetate

Cat.No: TP1153L

Synonym: Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate

Target: Others

Endothelin-2 (49-69), human TFA

Cat.No: TP2143

Synonym: Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA

Target: Others

Histone H3 (21-44)

Cat.No: T38785

Synonym: Histone H3 (21-44)

Endothelin-3, human, mouse, rabbit, rat

Cat.No: TP1175

Synonym: Endothelin 3 (Rat,Human)

Mad1 (6-21) (TFA)

Cat.No: T81885

Endothelin 3 (Rat,Human) (TFA)

Cat.No: TP1173

Synonym: Endothelin-3, human, mouse, rabbit, rat TFA

Histone H3 (1-21)

Cat.No: T40993

Synonym: Histone H3 (1-21)

2-Amino-4-(ethylthio)butanoic acid

Cat.No: T66823

Cat.No: TP1782

Acetyl-Heme-Binding Protein 1 (1-21) (human)

Cat.No: T83193

ELAAWCRWGFLLALLPPGIAG TFA

Cat.No: T82484

ELAAWCRWGFLLALLPPGIAG

Cat.No: T82485

BNP (1-21), Pro (Human)

Cat.No: T82847

Histone H3 (21-44)-GK-biotin (trifluoroacetate salt)

Cat.No: T36576

Synonym: Histone H3 (21-44)-GK-biotin (trifluoroacetate salt)

Forigerimod TFA

Cat.No: T73651

Cat.No: T75878

Cat.No: T38077

Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)

Cat.No: T36979

Synonym: Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)

Cat.No: T9427

Target: Others

Cat.No: T73650

N-Arachidonoyl Taurine

Cat.No: T35918

Cat.No: T83742

Synonym: Spike Binding Peptide 1

CC 401 dihydrochloride

Cat.No: T36673

Cat.No: T36695

Cat. No.	Product Name	Target	Signaling Pathways
TJS0341	7-Amino-4-(trifluoromethyl)coumarin 香豆素151,Coumarin 151,AFC,7-氨基-4-（三氟甲基）香豆素	5-HT Receptor	GPCR/G Protein; Neuroscience
	7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) 是一种荧光标记物，其激发和发射波长分别为400和500 nm，可用来灵敏的检测蛋白酶。

天然产物

7-Amino-4-(trifluoromethyl)coumarin

Cat.No: TJS0341

Synonym: 香豆素151,Coumarin 151,AFC,7-氨基-4-（三氟甲基）香豆素

Target: 5-HT Receptor

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