Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9997 |
GLL 398
|
Estrogen Receptor/ERR | Endocrinology/Hormones |
GLL 398 是一种具有口服活性的选择性雌激素受体降解剂,IC50 为 1.14 nM。 GLL 398 在异种移植乳腺癌模型中阻断肿瘤生长。 | |||
T31936 |
GLL398
GLL 398,GLL-398 |
||
GLL398 is an oral selective estrogen receptor down-regulating agent that strongly binds to ERα (IC50 =1.14 nM) and effectively degrades ERα in MCF-7 breast cancer cells (IC50 = 0.21 μM). |