Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16113 | ML753286 | AMPK | Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (IC50: 0.6 μM). It is also stable in plasma across species. | |||
T10490 |
(S)-ML753286
|
Others | Others |
(S)-ML753286 is a breast cancer resistance protein (BCRP) inhibitor (IC50: 0.6 μM on BCRP efflux transporter). |